Reproductive | Synthecon

Research Publications / Reproductive

A major effect of simulated microgravity on several stages of preimplantation mouse development is lethality associated with elevated phosphorylated SAPK/JNK.	Wang Y1, Xie Y, Wygle D, Shen HH, Puscheck EE, Rappolee DA.	Reprod Sci. 2009 Oct;16(10):947-59. doi: 10.1177/1933719109337544. Epub 2009 Jun 22.
A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance	McConkey CA1, Delorme-Axford E, Nickerson CA, Kim KS, Sadovsky Y, Boyle JP, Coyne CB	Sci Adv. 2016 Mar 4;2(3):e1501462. doi: 10.1126/sciadv.1501462. eCollection 2016
Direct effects of microgravity on testicular function: analysis of hystological, molecular and physiologic parameters	Ricci G, Esposito R, Catizone A, Galdieri M	J Endocrinol Invest 31:229-237, 2008
Effect Of Microgravity On Aromatase Expression In Sertoli Cells	Cirelli E1, De Domenico E, Botti F, Massoud R, Geremia R, Grimaldi P	Sci Rep. 2017 Jun 14;7(1):3469. doi: 10.1038/s41598-017-02018-2
Effect of Culture in Simulated Microgravity on the Development of Mouse Embryonic Testes	Nowacki D, Klinger FG, Mazur G, Felici MD	Adv Clin Exp Med. 2015 Sep-Oct;24(5):769-74. doi: 10.17219/acem/27920
Human Ovarian Cancer Multicellular Spheroids: A Model for Testing Antiproliferation Activity of Devil's Club (Oplopanax horridus) and Anticancer Agents	Tai J, Cheung SS, Hasman D	Planta Med. 2014 Jun;80(8-9):662-70. doi: 10.1055/s-0034-1368506
Human three-dimensional endometrial epithelial cell model to study host interactions with vaginal bacteria and Neisseria gonorrhoeae	Łaniewski P, Gomez A, Hire G, So M, Herbst-Kralovetz MM	Infect Immun. 2017 Jan 4. pii: IAI.01049-16. doi: 10.1128/IAI.01049-16
IL-36γ Augments Host Defense and Immune Responses in Human Female Reproductive Tract Epithelial Cells	Sean M. Winkle, Andrea L. Throop and Melissa M. Herbst-Kralovetz.	Front. Microbiol., 17 June 2016 \| http://dx.doi.org/10.3389/fmicb.2016.00955
In Vitro Growth of Mouse Preantral Follicles Under Simulated Microgravity	Zhang S, Wu Y, Weng Y, Xu Z, Chen W, Zheng D, Lin W, Liu J, Zhou Y.	J Vis Exp. 2017 Dec 17;(130). doi: 10.3791/55641.
In vitro model of placental trophoblast differentiation and cytomegalovirus infection	Swan KF, Ferris M, Pridjian G, Morris CA, Sullivan DE	Pregnancy Hypertens. 2015 Jan;5 (1): 155-6. doi: 10.1016/j.preghy.2014.10.323
Microbial Products Alter the Expression of Membrane-Associated Mucin and Antimicrobial Peptides in a 3-D Human Endocervical Epithelial Cell Model.	Radtke AL, Quayle AJ, Herbst-Kralovetz MM	Biol Reprod. 2012 Dec 6;87(6):132. doi: 10.1095/biolreprod.112.103366. Print 2012 Jun.
Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells	Pellegrini M, Di Siena S, Claps G, Di Cesare S, Dolci S, Rossi P, Geremia R, Grimaldi P	PLoS One 4:5(2):e9064, 2010
Mouse undifferentiated spermatagonial stem cells cultured as aggregates under simulated microgravity	Zhang X, Li L, Bai Y, Shi R, Wei H, Zhang S	Andrologia. 2014 Nov;46(9):1013-21. doi: 10.111/and.12189.
Mycoplasma genitalium Infection Activates Cellular Host Defense and Inflammation Pathways in a 3-Dimensional Human Endocervical Epithelial Cell Model	McGowin CL, Radtke AL, Abraham K, Martin DH, Herbst-Kralovetz M	J Infect Dis. 2013 Jun;207(12):1857-68. doi: 10.1093/infdis/jit101
Simulated Microgravity Using a Rotary Culture System Compromises the In Vitro Development of Mouse Preantral Follicles	Zhang S, Zheng D, Wu Y, Lin W, Chen Z, Meng L, Liu J, Zhou Y1	PLoS One. 2016 Mar 10;11(3):e0151062. doi: 10.1371/journal.pone.0151062. eCollection 2016
Tail-suspended model simulating mouse oocytes maturation inhibited with microgravity.	Wu C, Li L, Wei H, Wu Z, Jiang Q, Zhang S.	Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2012 Aug;29(4):687-90, 696. (Article in Chinese)